The Adventures of Nero Wolfe is a 1943–44 American radio drama series produced by Himan Brown and featuring Rex Stout’s fictional detective. Three actors portrayed Nero Wolfe over the course of the series. J. B. Williams starred in its first incarnation, beginning April 10, 1943, on the regional New England Network. Santos Ortega assumed the role when the suspense drama moved to ABC on July 5, 1943, and continued as Wolfe until sometime in 1944 when he was succeeded by Luis Van Rooten. Archie Goodwin, Wolfe’s assistant and legman, was played by Joseph Julian. Based on Stout’s principal characters but not his stories, the series ended with the broadcast July 14, 1944.